[Sodium salicylate induced intracellular Ca2+ concentration change in guinea pig outer hair cells].


OBJECTIVE In order to explore the mechanism of sodium salicylate ototoxicity the effect of sodium salicylate on intracellular Ca2+ ([Ca2+]i) of the outer hair cells (OHCs) and the effects of calcium channel antagonist on sodium salicylate-induced [Ca2+]i changes of the OHCs were examined. METHODS The OHCs of guinea pig cochlear were isolated using an… (More)