[Small interfering RNA-mediated RIP1 knockdown enhances L-OHP sensitivity of human oral squamous carcinoma cells].

@article{Xu2013SmallIR,
  title={[Small interfering RNA-mediated RIP1 knockdown enhances L-OHP sensitivity of human oral squamous carcinoma cells].},
  author={Jin-cheng Xu and Yingying Huang and Yang Li and Longjian Pu and Fei Xia and Chenchen Jiang and Hao Liu and Zhiwen Jiang},
  journal={Nan fang yi ke da xue xue bao = Journal of Southern Medical University},
  year={2013},
  volume={33 7},
  pages={1004-7}
}
OBJECTIVE To investigate the effect of small interfering RNA-mediated receptor-interacting protein kinase 1 (RIP1) knockdown on the sensitivity of human oral squamous carcinoma cells to to oxaliplatin (L-OHP)-induced apoptosis and explore a new target for clinical treatment of oral squamous carcinoma. METHODS The viability of human oral squamous carcinoma cell line KB exposed to different concentrations (0, 0.25, 0.5, 1, 2, 4 µmol/L) of L-OHP were detected by MTT assay. PI/Annexin V staining… CONTINUE READING
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