[Signal transduction and drug development].

  • Hitoshi Kurose
  • Published 2002 in
    Nihon rinsho. Japanese journal of clinical…


Extracellular information is translated into the cellular responses by various signal transduction systems such as G protein-coupled receptor-linked and protein tyrosine kinase receptor-mediated pathways. The changes or modifications of theses signaling proteins cause uncontrolled transformation or cell death. One of the features of the signaling molecules… (More)


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