[Sibutramine--antidepressive agent tested against obesity].

  title={[Sibutramine--antidepressive agent tested against obesity].},
  author={Stephan R{\"o}ssner},
  volume={98 15},
Eight European centers recruited 605 obese patients (BMI 30-45 kg/m2) for a six month period of weight loss with sibutramine (10 mg/d) combined with an individualized 600 kcal/d deficit. 467 (77%) patients with > 5% weight loss were then randomized to sibutramine (10 mg/day) and placebo groups over a further 18 months. Initially weight loss progressed to a… CONTINUE READING