[Sharp changes in the copy number of mtDNA and its transcription in the blood cells of X-ray irradiated mice are observed, and mtDNA fragments appear in the blood serum].

@article{Evdokimovskii2007SharpCI,
  title={[Sharp changes in the copy number of mtDNA and its transcription in the blood cells of X-ray irradiated mice are observed, and mtDNA fragments appear in the blood serum].},
  author={Edward V. Evdokimovskii and M V Patrushev and Tatjana E Ushakova and Azhub I. Gaziev},
  journal={Radiatsionnaia biologiia, radioecologiia},
  year={2007},
  volume={47 4},
  pages={
          402-7
        }
}
Changes in the number of mitochondrial DNA (mtDNA) copies and alterations in its transcription were followed in the blood cells of mice after their exposure to X-rays; also, extracellular mtDNA fragments were registered in the blood serum of these mice. By a real time polymerase chain reaction (RT-PCR), a sharp increase in mtDNA copy number one hour after the exposure was detected in the blood cells of 1 Gy X-ray irradiated mice. This increase in mtDNA copies is considered as a result of a… CONTINUE READING

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