[Severe bradycardia and asystole with low dose sufentanil during induction with sevoflurane: a report of three cases].

@article{Cardinal2004SevereBA,
  title={[Severe bradycardia and asystole with low dose sufentanil during induction with sevoflurane: a report of three cases].},
  author={Val{\'e}rie Cardinal and Ren{\'e} Martin and J M Tetrault and M J Colas and Linda Gagnon and Yves Claprood},
  journal={Canadian journal of anaesthesia = Journal canadien d'anesthesie},
  year={2004},
  volume={51 8},
  pages={806-9}
}
OBJECTIVES In a randomized double blind clinical study using low doses of fentanyl or sufentanil during sevoflurane induction, we observed three cases of severe bradycardia, forcing us to discontinue the study. We wish to describe these three cases. CLINICAL DATA Anesthesia was induced in the three patients, using a single breath technique consisting of a mixture of sevoflurane 8% with a nitrous oxide flow of 3 L x min(-1) and an oxygen flow of 3 L x min(-1). After the patients had lost… CONTINUE READING

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