[Sensitive determination of vitamin K analogues in biological samples by high-performance liquid chromatography using platinum catalyst reduction and electrochemical detection].

Abstract

To investigate the physiological roles of vitamin K analogues in bone metabolism, especially in osteoporosis, we have developed a sensitive and simple analysis system for vitamin K analogues in the serum and bone. After the separation of vitamin K analogues on a reversed-phase column, the analogues were reduced once in a platinum catalyst reduction column… (More)

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