Corpus ID: 10572484

[Screening of hepatocellular carcinoma: role of the alpha-fetoprotein (AFP) and ultrasonography].

@article{Barletta2005ScreeningOH,
  title={[Screening of hepatocellular carcinoma: role of the alpha-fetoprotein (AFP) and ultrasonography].},
  author={Emiddio Barletta and Vincenza Tinessa and Bruno Daniele},
  journal={Recenti progressi in medicina},
  year={2005},
  volume={96 6},
  pages={
          295-9; quiz 328
        }
}
  • Emiddio Barletta, Vincenza Tinessa, Bruno Daniele
  • Published in Recenti progressi in medicina 2005
  • Medicine
  • Even if there are no definitive evidence that hepatocellular carcinoma (HCC) screening in high-risk groups improves survival, many physicians screen high-risk population by various strategies, alpha-fetoprotein (AFP) and liver ultrasonography are the most widely used tools. AFP sensitivity and specificity depend on the cut-off value chosen. In cirrhotic patients, using a cut-off level of 20 ng/mL, sensitivity is only around 60% and positive predictive value ranges from 9% to 50%, depending on… CONTINUE READING

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