[Screening of drugs inhibiting cholesterol synthesis].

  • M B Bibikova
  • Published 1997 in
    Antibiotiki i khimioterapiia = Antibiotics and…

Abstract

The biosynthesis of fusidin, an antibiotic of steroid structure, was used as a model of steroid synthesis. Screening of compounds modifying the fusidin synthesis included 80 strains of mycelial fungi. A high frequency of such fungal cultures was observed. 9 cultures forming compounds which inhibited the synthesis of cholesterol in the cell culture of human… (More)

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