[Screening and analysis of in vivo induced genes of Mycobacterium tuberculosis].

OBJECTIVE To screen in vivo induced genes of Mycobacterium tuberculosis and search possible molecular targets of new drugs, vaccines, and early diagnostic methods. METHODS In vivo induced antigen technology (IVIAT) was used in this study. Genomic DNA from M. tuberculosis of the strain H37Rv was extracted. The DNA was partially digested with Sau3A I and… CONTINUE READING