[Saponin from Tupistra chinensis Baker inhibits mouse sarcoma S-180 cell proliferation in vitro and implanted solid tumor growth in mice].

@article{Cai2007SaponinFT,
  title={[Saponin from Tupistra chinensis Baker inhibits mouse sarcoma S-180 cell proliferation in vitro and implanted solid tumor growth in mice].},
  author={Jing Cai and Zheng-guang Zhu and Chuan-lin Yu and Lin-sheng Lei and Shu-guang Wu},
  journal={Nan fang yi ke da xue xue bao = Journal of Southern Medical University},
  year={2007},
  volume={27 2},
  pages={188-90, 194}
}
OBJECTIVE To study the antitumor effect of saponin extracted from Tupistra chinensis Baker (STCB) against mouse sarcoma S-180 cell proliferation in vitro and in vivo and explore the primary mechanism of this effect. METHODS Cytotoxic effect of STCB on S-180 cells in vitro was evaluated by MTT colorimetry, and its effect against in vitro tumor growth was tested in Kunmin mice bearing S-180 implanted tumor. The morphological and ultrastructural changes of S-180 cells after saponin treatment in… CONTINUE READING