[Roles of surfactant protein A (SP-A) and phospholipids on regulation of surfactant secretion from alveolar type II epithelial cells].

Abstract

Surfactant protein A (SP-A) is known to inhibit surfactant secretion from pulmonary alveolar type II epithelial cells (type II cells). It is unknown whether SP-A acts as an inhibitor in the presence of lipids since SP-A mostly exists complexed with surfactant lipids. In this paper we focused on this issue using purified surfactant, purified SP-A and… (More)

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