[Role of three-color flow cytofluorometry in the algorithm for detection of minimal residual disease in children with acute lymphoblastic and acute myeloblastic leukemia].

@article{Savva2009RoleOT,
  title={[Role of three-color flow cytofluorometry in the algorithm for detection of minimal residual disease in children with acute lymphoblastic and acute myeloblastic leukemia].},
  author={Natalia N Savva and Michael V Belevtsev and V. P. Savitskii and N V Migal' and Ludmila V Movchan and Olga V. Aleinikova},
  journal={Klinicheskaia laboratornaia diagnostika},
  year={2009},
  volume={12},
  pages={
          15-8
        }
}
Three-color flow cytofluorometry (FCF) was used to identify minimal residual disease in 124 patients with acute lymphoblastic leukemia (ALL) treated in accordance with the ALL-myeloblastic leukemia (MBL)-2002/2008 protocol and 36 patients with MBL treated under the MBL-MM-2000 protocol. It was shown that approximately a fifth of children with ALL, 3-color FCF could not monitor minimal residual disease, which required the use of 4- or more-color FCF and parallel determination in these MBL… CONTINUE READING

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