[Role of aromatic amines in the induction of tumors of the urinary tract. Experimental evaluation of the DNA damage induced with naphthylamines].


DNA damage induced by 1-Naphtylamine and 2-Naphtylamine has been verified using alkaline elution technique. Single-stranded DNA breaks were evident in the liver and kidneys of mice treated within 4 hours from the injection. A difference in the organotropism of the two aromatic amines has been observed. These results improve the applicability of the… (More)


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