[Role of NO-mediated mechanisms in post-irradiation changes of neurohormonal regulation of the heart function].

Abstract

Investigations on isolated Langendorff-perfused rat heart have shown that after the impact of ionizing radiation in 1 Gy dose the myocardial contractility and relaxation are decreased. The inhibition of NO synthesis attenuates chrono- and inotropic responses of the heart and reaction of coronary vessels to norepinephrine (NE), increases negative inotropic… (More)

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@article{Lobanok2004RoleON, title={[Role of NO-mediated mechanisms in post-irradiation changes of neurohormonal regulation of the heart function].}, author={L. M. Lobanok and T. A. Suvorova}, journal={Radiatsionnaia biologiia, radioecologiia}, year={2004}, volume={44 3}, pages={312-8} }