[Role of CD44 in monocyte transmigration across Cryptococcus neoformans-infected blood-brain barrier in vitro].


OBJECTIVE To explore the role of CD44 in monocyte adhesion to human brain microvascular endothelial cells (HBMECs) and monocyte migration across an in vitro model of blood-brain barrier (BBB) infected by Cryptococcus neoformans (Cn). METHODS An in vitro blood-brain barrier model was constructed using a transwell chamber covered with a HBMEC monolayer. The… (More)