[Risk factors conditioning the incidence and severity of cyclosporine A-induced gingival overgrowth and methods of prevention].

@article{Bartoli2004RiskFC,
  title={[Risk factors conditioning the incidence and severity of cyclosporine A-induced gingival overgrowth and methods of prevention].},
  author={Francesco Bartoli and Gaetano Castronovo and Achille Stabile},
  journal={Minerva stomatologica},
  year={2004},
  volume={53 4},
  pages={165-70}
}
Cyclosporin A (CsA) induced gingival overgrowth is one of the major side-effects conditioning the quality of life of the patient under immunosuppressive therapy. This adverse effect has been first reported in 1983 and affects almost 30% of treated patients. Several papers have been published concerning the cellular/molecular mechanisms by which CsA may induce, at the same time, an immunosuppressive and proliferative action. In this review various factors concerning the patient and his milieu… CONTINUE READING