[Rilmenidine sympatholytic activity preserves mental and orthostatic sympathetic response and epinephrine secretion].
@article{Esler2004RilmenidineSA, title={[Rilmenidine sympatholytic activity preserves mental and orthostatic sympathetic response and epinephrine secretion].}, author={M. Esler and A. Lux and G. Jennings and J. Hastings and F. Socratous and G. Lambert}, journal={Archives des maladies du coeur et des vaisseaux}, year={2004}, volume={97 7-8}, pages={ 786-92 } }
BACKGROUND
Heightened central sympathetic nervous outflow is common in essential hypertension, contributing to hypertension development and perhaps also to complications. Acute sympathetic nervous activation is a proven trigger for adverse cardiovascular events. Accordingly, antihypertensive drugs inhibiting sympathetic outflow represent a theoretically attractive therapeutic option.
OBJECTIVES
To study the sympatholytic and blood pressure lowering activity of the imidazoline binding agent… CONTINUE READING
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