[Rhadboid tumours: hSNF/INI1 deficient cancers of early childhood with aggressive behaviour].

@article{Bourdeaut2010RhadboidTH,
  title={[Rhadboid tumours: hSNF/INI1 deficient cancers of early childhood with aggressive behaviour].},
  author={Franck Bourdeaut and Christelle Dufour and Olivier Delattre},
  journal={Bulletin du cancer},
  year={2010},
  volume={97 1},
  pages={37-45}
}
Rhabdoid tumours are rare aggressive tumours of infancy. The definition classically relies on a characteristic morphology and the inactivation of the hSNF5/INI1 tumour suppressor gene. This entity includes central nervous system tumours (ATRT), renal tumours (RTK) and soft-part tumours. Their rarity and morphological pleomorphism make the diagnosis often challenging. However, the recently introduced immunohistochemistry with anti-INI1 (anti-SMARCB1) antibody is a very useful diagnostic tool… CONTINUE READING