[Results of 1043 prenatal cytogenetic studies: retrospective study in the context of applicability of interphase FISH in prenatal diagnosis]].


OBJECTIVES The risk of aneuploidy in a fetus is the main reason for referral in approximately 80% of prenatal studies. Recently, a new method for rapid detection of the most frequent aneuploidies affecting chromosomes 13, 18, 21, X and Y has been developed. Fluorescence in situ hybridisation (FISH) on uncultured fetal cells with probes specific for these… (More)