[Regulation of the fetoplacental unit. 2. Circadian changes in the sensitivity of the fetal hypothalamo-hypophyseal system for the feedback effect of cortisol].

@article{Reck1988RegulationOT,
  title={[Regulation of the fetoplacental unit. 2. Circadian changes in the sensitivity of the fetal hypothalamo-hypophyseal system for the feedback effect of cortisol].},
  author={G. Reck and A. Klein and M. Breckwoldt},
  journal={Geburtshilfe und Frauenheilkunde},
  year={1988},
  volume={48 2},
  pages={
          99-101
        }
}
The present study investigates the significance of a circadian changing sensitivity on the feed back action of cortisol for the foetal hypothalamic hypophyseal system. 9 patients with uncomplicated courses of pregnancy in the 37th to 40th week volunteered in this study. All of them delivered healthy babies at term. 5 patients received a continuous infusion of 0.25 mg ACTH1-24 (Synacthen) in the morning from 10 a.m. to 4 p.m. (group I). To 4 patients an analogous ACTH infusion was applied in the… Expand