Corpus ID: 23480943

[Regulation of sonic hedgehog on vascular endothelial growth factor, basic fibroblast growth factor expression and secretion in bone marrow mesenchymal stem cells].

@article{Cai2012RegulationOS,
  title={[Regulation of sonic hedgehog on vascular endothelial growth factor, basic fibroblast growth factor expression and secretion in bone marrow mesenchymal stem cells].},
  author={Jiaqin Cai and Yizhou Huang and X. Chen and Honglei Xie and Y. Huang and L. Deng},
  journal={Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery},
  year={2012},
  volume={26 1},
  pages={
          112-6
        }
}
  • Jiaqin Cai, Yizhou Huang, +3 authors L. Deng
  • Published 2012
  • Biology, Medicine
  • Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • OBJECTIVE Sonic hedgehog (Shh) signaling pathway is involved in an important part of regulating angiogenesis. To investigate the effects of recombinant Shh N-terminate (rShh-N) on the expression and secretion of angiogenesis-related factor-vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF). METHODS Bone marrow mesenchymal stem cells (BMSCs) were isolated from 3-day-old healthy Sprague Dawley rats and cultured to passage 3 in vitro. rShh-N at the concentrations… CONTINUE READING
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