[Regulation of osteoclastic function through cell surface receptors].

@article{Kukita2003RegulationOO,
  title={[Regulation of osteoclastic function through cell surface receptors].},
  author={Toshio Kukita and Akiko Kukita},
  journal={Clinical calcium},
  year={2003},
  volume={13 4},
  pages={444-8}
}
Osteoclasts express various surface-molecules involved in the regulation of osteoclastic function as well as osteoclastogenesis. Receptor activator NF kappa B (RANK:the receptor for RANKL), IL-1 receptor and integrin alpha(v)beta(3) act as positive regulators of osteoclastic bone resorption. Blockage of their function results in the inhibition of bone… CONTINUE READING