[Regulation of key enzymes in tryptophan biosynthesis pathway in Escherichia coli].

Abstract

To improve tryptophan production in Escherichia coli, key genes in the tryptophan biosynthesis pathway -aroG, trpED, trpR and tnaA were manipulated. TrpR gene was knocked out to eliminate the repression on the key genes controlling tryptophan biosynthesis and transportation on bacteria chromosome, and the tryptophan degradation was blocked by tnaA gene… (More)

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Cite this paper

@article{Yu2008RegulationOK, title={[Regulation of key enzymes in tryptophan biosynthesis pathway in Escherichia coli].}, author={Jinlong Yu and Jing Wang and Jianxin Li and Changjiang Guo and Yingwu Huang and Qishou Xu}, journal={Sheng wu gong cheng xue bao = Chinese journal of biotechnology}, year={2008}, volume={24 5}, pages={844-50} }