Corpus ID: 45598546

[Regional cerebral blood flow measurements at pre- and post-Diamox test using split dose 99mTc-ECD SPECT: comparison with 133Xe inhalation method and linearization correction].

@article{Sogabe1997RegionalCB,
  title={[Regional cerebral blood flow measurements at pre- and post-Diamox test using split dose 99mTc-ECD SPECT: comparison with 133Xe inhalation method and linearization correction].},
  author={Ichiro Sogabe},
  journal={Kaku igaku. The Japanese journal of nuclear medicine},
  year={1997},
  volume={34 1},
  pages={
          35-44
        }
}
  • Ichiro Sogabe
  • Published in
    Kaku igaku. The Japanese…
    1997
  • Medicine
  • A new method for quantitative measurement of regional cerebral blood flow (rCBF) before and after acetazolamide (Diamox) administration was developed using 99mTc labeled ethyl cysteinate dimer (ECD) and consecutive SPECT with continuous arterial blood sampling. Moreover, the correction was proposed for underestimation of rCBF due to the inherent low first pass extraction of ECD in high blood flow regions. The rCBF values obtained by the microsphere model in 5 patients correlated well with those… CONTINUE READING

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