[Recent progress of midkine research on cancer].

  title={[Recent progress of midkine research on cancer].},
  author={Kenji Kadomatsu},
  journal={Nihon rinsho. Japanese journal of clinical medicine},
  volume={58 6},
  • Kenji Kadomatsu
  • Published 2000 in
    Nihon rinsho. Japanese journal of clinical…
Midkine is a heparin-binding growth factor, implicated in various biological phenomena such as neuronal survival and differentiation, tissue remodeling and carcinogenesis. Together with pleiotrophin, midkine constitutes a family that is distinct from other heparin-binding growth factors. In this review, I will briefly describe biochemical and biological characteristics of midkine and then focus on its biological significance in cancer. The most intriguing feature of midkine in cancer is its… CONTINUE READING


Publications citing this paper.
Showing 1-3 of 3 extracted citations

Similar Papers

Loading similar papers…