[Recent progress of midkine research on cancer].

@article{Kadomatsu2000RecentPO,
  title={[Recent progress of midkine research on cancer].},
  author={Kenji Kadomatsu},
  journal={Nihon rinsho. Japanese journal of clinical medicine},
  year={2000},
  volume={58 6},
  pages={
          1337-47
        }
}
  • Kenji Kadomatsu
  • Published 2000 in
    Nihon rinsho. Japanese journal of clinical…
Midkine is a heparin-binding growth factor, implicated in various biological phenomena such as neuronal survival and differentiation, tissue remodeling and carcinogenesis. Together with pleiotrophin, midkine constitutes a family that is distinct from other heparin-binding growth factors. In this review, I will briefly describe biochemical and biological characteristics of midkine and then focus on its biological significance in cancer. The most intriguing feature of midkine in cancer is its… CONTINUE READING

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