[Recent advances in pathophysiology and treatment of acute ischemic stroke].

  • Yasuo Fukuuchi
  • Published 1998 in Rinsho shinkeigaku = Clinical neurology


The pathophysiology of ischemic neuronal cell damage has been studied extensively. Intracellular calcium ions, excitatory amino acids, nitric oxide, oxygen free radicals, proteolysis, apoptosis, and so on play important roles. There are also gene expressions following cerebral ischemia, such as the immediately early gene, heat shock protein, cytokines… (More)


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