[RANKL and OPG expression in bone marrow-derived mesenchymal stem cells of ovariectomied promotes osteoclast development and enhances its function].

Abstract

OBJECTIVE To investigate the expression of receptor activator of nuclear factor-kappa B lig (RANKL), osteoprotegerin (OPG) in bone marrow mesenchymal stem cells (BMSCs) and its impact on osteoclast formation and function in the ovariectomied mice. METHODS An animal model of osteoporosis was established by ovariectomy (OVX bilateral ovarian resection) in 8… (More)

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