[RANKL/RANK signaling in rheumatoid arthritis].

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease, which is induced by abundant inflammatory cytokines releasing from synovial fibroblasts and T lymphocytes. These cytokines differentiate monocyte-macrophage lineage cells to mature osteoclasts, which cause bone resorption and then joint destruction. RANKL is involved in the development of… (More)

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Cite this paper

@article{Omata2011RANKLRANKSI, title={[RANKL/RANK signaling in rheumatoid arthritis].}, author={Yasunori Omata and Sakae Tanaka}, journal={Clinical calcium}, year={2011}, volume={21 8}, pages={1175-80} }