• Medicine
  • Published in Annales de biologie clinique 2000

[Pseudoleucopenia due to in vitro leukocyte agglutination polynuclear neutrophils: experience of a laboratory, review of the literature and future management].

@article{Lesesve2000PseudoleucopeniaDT,
  title={[Pseudoleucopenia due to in vitro leukocyte agglutination polynuclear neutrophils: experience of a laboratory, review of the literature and future management].},
  author={Jean-François Lesesve and Xavier Haristoy and M. A. Thouvenin and V{\'e}ronique Latger-Cannard and Jacqueline Buisine and Thomas Pierre Lecompte},
  journal={Annales de biologie clinique},
  year={2000},
  volume={58 4},
  pages={
          417-24
        }
}
Leukoagglutination is a rare EDTA-dependent phenomenon resulting in a spurious minoration of the leukocyte count performed using automated analyzers. We described seven cases. The leukocyte agglutination was detected by unstable WBC count, abnormal WBC histograms and presence of clusters of polymorphonuclears on the smear. PMN aggregates of 3 to 10 cells or bigger were observed. Discrepancies between the erroneous automated WBC count and the real count were moderate in most cases… CONTINUE READING