[Proteinkinase MAK-V/Hunk as a possible dianostic and prognostic marker of human breast carcinoma].

@article{Korobko2004ProteinkinaseMA,
  title={[Proteinkinase MAK-V/Hunk as a possible dianostic and prognostic marker of human breast carcinoma].},
  author={Igor V. Korobko and Larisa E. Zavalishina and Sergei L. Kiselev and Natan T Raikhlin and G. A. Frank},
  journal={Arkhiv patologii},
  year={2004},
  volume={66 5},
  pages={6-9}
}
We propose a system for detection of overproduction of protein kinase MAK-V/Hunk in tumours. MAK-V/ Hunk overproduction is observed in about 50% breast carcinomas. Positive staining is obseved in tumour cells only and has mainly cytoplasmic characteristics. Increased production of MAK-V/Hunk does not correlate with histological type of carcinoma, metastasizing, steroid receptor status (estrogen and progesterone), proliferative activity. Tumours positive for MAK-V/ Hunk were more frequently… CONTINUE READING