[Protective effect of exogenous superoxide dismutase against rat midbrain dopaminergic neuron apoptosis induced by 6-hydroxydopamine].

Abstract

OBJECTIVE To observe the changes of total antioxidant ability of rat midbrain and T-superoxide dismutase (T-SOD) activity, and define the relation between oxidative stress and dopaminergic neuron apoptosis induced by 6-hydroxydopamine (6-OHDA), observing also the protection of the exogenous SOD against the neuron apoptosis. METHODS A total of 144 SD rats… (More)

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