[Proteasomes: their role in cellular processes].

  title={[Proteasomes: their role in cellular processes].},
  author={Anna S. Tsimokha},
  volume={52 4},
The presented review concerns the structure functional analysis of proteasomes and the participation of ubiquitin proteasome system in the basic cellular processes. 26S proteasomes is a key enzyme of the ubiquitin-dependent pathway of protein degradation in cells. This protein particle is composed of 20S catalytic core and associated regulatory complexes. In addition to several types of peptidase activities, eukaryotic proteasomes also have endoribonuclease, protein-chaperone and DNA-helicase… CONTINUE READING