[Prophylactic efficacy of a basidiomycetes preparation AHCC against lethal Candida albicans infection in experimental granulocytopenic mice].

@article{Ikeda2003ProphylacticEO,
  title={[Prophylactic efficacy of a basidiomycetes preparation AHCC against lethal Candida albicans infection in experimental granulocytopenic mice].},
  author={Tatsuo Ikeda and Hiroko Ishibashi and Ryuichi Fujisaki and Masatoshi Yamazaki and Kohji Wakame and Kenichi Kosuna and Hideyo Yamaguchi and Yasuo Ono and Shigeru Abe},
  journal={Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology},
  year={2003},
  volume={44 2},
  pages={
          127-31
        }
}
The prophylactic effects of a Basidiomycetes preparation, AHCC, against lethal Candida albicans infection were investigated in non treated or immunosuppressed mice. In the cyclophosphamide-or 5-fluorouracil (5-FU)-treated leukopenic mice and nontreated mice, the intraperitoneal administration of AHCC prior to C. albicans infection clearly prolonged the survival periods of the infected mice. In doxorubicin-treated mice, AHCC was less but significantly effective. On the other hand, in… CONTINUE READING
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