[Properties of hypoxanthineguanine-phosphoribosyltransferase (HGPRTase) in a gout patient with partial deficiency of this enzyme (author's transl)].

@article{Grbner1979PropertiesOH,
  title={[Properties of hypoxanthineguanine-phosphoribosyltransferase (HGPRTase) in a gout patient with partial deficiency of this enzyme (author's transl)].},
  author={Wolfgang Gr{\"o}bner and Nepomuk Z{\"o}llner},
  journal={Klinische Wochenschrift},
  year={1979},
  volume={57 2},
  pages={63-8}
}
Some physicochemical properties of HGPRTase were studied in hemolysates and fibroblasts of a gout patient with partial deficiency of this enzyme. In comparison to normal HGPRTase the mutant enzyme from erythrocytes was found to have an elevated apparent Km-value for hypoxanthine and guanine and a lower Km-value for PRPP. The patient's enzyme from erythrocytes is more stable at +4 degrees C and +80 degrees C, the enzyme from fibroblasts more labile than that of controls. The inhibition of the… CONTINUE READING

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Some physicochemical properties of HGPRTase were studied in hemolysates and fibroblasts of a gout patient with partial deficiency of this enzyme .
[ Properties of hypoxanthineguanine - phosphoribosyltransferase ( HGPRTase ) in a gout patient with partial deficiency of this enzyme ( author 's transl ) ] .
[ Properties of hypoxanthineguanine - phosphoribosyltransferase ( HGPRTase ) in a gout patient with partial deficiency of this enzyme ( author 's transl ) ] .
Some physicochemical properties of HGPRTase were studied in hemolysates and fibroblasts of a gout patient with partial deficiency of this enzyme .
[ Properties of hypoxanthineguanine - phosphoribosyltransferase ( HGPRTase ) in a gout patient with partial deficiency of this enzyme ( author 's transl ) ] .
[ Properties of hypoxanthineguanine - phosphoribosyltransferase ( HGPRTase ) in a gout patient with partial deficiency of this enzyme ( author 's transl ) ] .
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