[Promising directions of search for antihypoxants and targets of their action].

Abstract

The modem notions about mechanisms of the organism adaptation to hypoxia are reviewed. Promising new directions in the search for effective medicinal agents with antihypoxant action are proposed. Probable targets for antihypoxant action, including mitochondrial ATP-dependent potassium channel (mito-KATP), mitochondrial megapore (mPTP), and hypoxia-inducible… (More)

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