Corpus ID: 37609784

[Proliferation inhibition of glioma cells by vitamin K2].

  title={[Proliferation inhibition of glioma cells by vitamin K2].},
  author={L. Sun and Y. Yoshii and K. Miyagi and A. Ishida},
  journal={No shinkei geka. Neurological surgery},
  volume={27 2},
  • L. Sun, Y. Yoshii, +1 author A. Ishida
  • Published 1999
  • Medicine
  • No shinkei geka. Neurological surgery
  • The antitumor effects of vitamin K2 were studied using three glioma cell lines: C6 (rat glioma cell), RBR17T and T98G (human glioma cell). The antitumor effects were estimated by count assay. The results was that vitamin K2 induced growth inhibition in a dose-dependent manner. The RBR 17T cells exposed to vitamin K2 for 72 hours resulted in oligonucleosomal DNA fragmentation and formed a ladder on agarose gel electrophoresis. Furthermore, the RBR17T cells exposed to vitamin K2 for 24 hours were… CONTINUE READING
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