[Prognostic significance and clinic utility of serum and immunohistochemical cathepsin B levels in colorectal cancer].

@article{Padilla2003PrognosticSA,
  title={[Prognostic significance and clinic utility of serum and immunohistochemical cathepsin B levels in colorectal cancer].},
  author={David Padilla and Te{\'o}filo Cubo and Jos{\'e} Ma Molina and Miguel Angel Bonillo Garc{\'i}a and Gabriel de la Osa and Teodoro Palomino and R. B. Pardo and Jorge Martin and Eugenio Ar{\'e}valo and J Hern{\'a}ndez Calvo},
  journal={Anales de medicina interna},
  year={2003},
  volume={20 10},
  pages={521-5}
}
BACKGROUND Aproximately one third of node-negative colorectal cancer recur suggesting the presence of micrometastasis not detected by conventional histopathologic methods. We think that the role of enzymes like Cathepsin B play in the process of invasion and metastasis in colorectal cancer might identify at earlier stages patients with high risk of shorter survival and who need more aggressive treatment. Our porpuse is to evaluate the prognostic significance of preoperative serum and… CONTINUE READING