[Prognostic importance of lactate dehydrogenase (LDH) in oncology].

Abstract

Glycolysis is increased in most of the malignant cells, providing the largest proportion of energy needed for cell proliferation. Lactate dehydrogenase (LDH) catalyses the reversible process of pyruvate to lactate in anaerobic condition. LDHA isoenzyme expressed mainly by malignant cells, significantly increases lactate formation. Lactate induces the… (More)
DOI: 10.1556/650.2017.30890

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