[Progesterone-induced microRNA-1a inhibits the proliferation of endometrial epithelial cells].

@article{Pan2016ProgesteroneinducedMI,
  title={[Progesterone-induced microRNA-1a inhibits the proliferation of endometrial epithelial cells].},
  author={Jun-li Pan and Dong-zhi Yuan and Li jia Nie and Jin-hu Zhang and Li-min Yue},
  journal={Sheng li xue bao : [Acta physiologica Sinica]},
  year={2016},
  volume={68 6},
  pages={716-724}
}
The aim of the present study was to investigate the effects of progesterone (P4)-induced microRNA-1a (miR-1a) on the proliferation of endometrial epithelial cells (EECs) and the underlying mechanism. In vivo, following subcutaneous injection of estradiol (E2) alone (E2 group) or combined injections of E2 and P4 (E2P4 group) in ovariectomized mice, quantitative real-time PCR (qPCR) was used to check the expression of miR-1a-3p in the directly isolated mouse EECs. The agomir or antagomir specific… CONTINUE READING