[Production and characterization of a monoclonal antibody that selectively marks the astrocyte population in the central nervous system].

@article{Gost1993ProductionAC,
  title={[Production and characterization of a monoclonal antibody that selectively marks the astrocyte population in the central nervous system].},
  author={Javier Gost and Ricardo Insausti and Luis M. Gonzalo},
  journal={Revista de medicina de la Universidad de Navarra},
  year={1993},
  volume={38 2},
  pages={9-20}
}
The development of a monoclonal antibody that selectively labels the astrocitic population of the central nervous system in the three species tested (human, monkey and rat) is described. The tissue used as immunogen consisted in a sector of the human hippocampus (CA1) from a brain removed shortly after death. The neuropathological examination in this case revealed an congophilic angiopathy. The tissue was frozen until homogenezation and intraperitoneal injection in 8 weeks old BALB/C mice… CONTINUE READING