[Process of sodium fusidate inactivation as affected by oxygen and humidity].


The effect of oxygen and moisture on stability of sodium fusidate was studied. It was shown that inactivation of the antibiotic in the atmosphere of oxygen was due to its oxidation in the preparations with low humidity levels. In the preparations with high humidity levels, the main cause of the antibiotic inactivation was hydrolysis with respect to C-16-O… (More)