[Preventive effects of 5-hydroxy-1-methylhydantoin on paraquat-induced nephrotoxicity in rat].


OBJECTIVE To investigate the protective effects of 5-hydroxy-1-methylhyantoin (HM ) on paraquat (PQ)-induced nephrotoxicity in rat and its possible mechanism. METHODS Twenty-four male Sprague-Dawley (SD) rats were randomly divided into four groups: namely control, PQ, vitamin C and HMH groups, with 6 rats in each group. The rats in control group were… (More)
DOI: 10.3760/cma.j.issn.2095-4352.2015.04.004