[Preparation of silybin-phospholipid complex and its bioavailability in rats].

  title={[Preparation of silybin-phospholipid complex and its bioavailability in rats].},
  author={Yan-yu Xiao and Yun-mei Song and Zhi-Peng Chen and Qi-neng Ping},
  journal={Yao xue xue bao = Acta pharmaceutica Sinica},
  volume={40 7},
AIM To prepare silybin-phospholipid complex and study its physicochemical properties. To compare the pharmacokinetic characteristics and bioavailability after oral administration of silybinphospholipid complex and silybin material in rats. METHODS Using acetone as a reaction medium, silybin and phospholipid were resolved into the medium, when the organic solvent was clear, then removed under vacuum evaporation, silybin-phospholipid complex was obtained. The new complex' s physicochemical… CONTINUE READING


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