[Preparation of cyclosporine A pH sensitive nanoparticles and oral pharmacokinetics in rats].

Abstract

AIM To study the preparation conditions and its oral pharmacokinetic characteristics of cyclosporine A (CyA) pH sensitive nanoparticles. METHODS The CyA pH sensitive nanoparticles were prepared by the quasi-emulsion solvent diffusion technique (QESD). Male Sprague-Dawley (SD) rats weighing (250 +/- 20) g were selected and randomly divided into five groups… (More)

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@article{Dai2004PreparationOC, title={[Preparation of cyclosporine A pH sensitive nanoparticles and oral pharmacokinetics in rats].}, author={Jun-dong Dai and Xue-qing Wang and Tao Zhang and Meng Meng and Xuan Zhang and Wan-liang L{\"u} and Qiang Zhang}, journal={Yao xue xue bao = Acta pharmaceutica Sinica}, year={2004}, volume={39 12}, pages={1023-7} }