[Preparation and evaluation of microbubble ultrasound contrast agent with N-carboxymethyl chitosan].

OBJECTIVE To prepare microbubble, made of N-carboxymethyl chitosan, as ultrasound contrast agent and evaluate its characteristics and acoustic effects in vivo. METHODS Oil-Water-Oil multiple emulsion/solvent evaporation method was used to prepare the microbubble contrast agent. Both optical micrography and scanning electron micrography were performed to… CONTINUE READING