[Prenatal alpha fetoprotein screening for defects in the neural tube].

  • Philipp Grob
  • Published 1978 in Schweizerische medizinische Wochenschrift


Abnormally increased alpha1-fetoprotein (AFP) in the serum of women in the 16th--18th week of pregnancy defines a group of individuals with a high risk for open neural tube defects (spina bifida and anencephaly). Repeated measurement of AFP, ultrasound and further clinical examination serve to exclude other situations associated with high serum AFP such as… (More)