[Precocious puberty caused by hCG-producing germinoma involving the bilateral basal ganglia and cerebral white matter without 1ypical radiologic findings: case report].

@article{Sugiyama2006PrecociousPC,
  title={[Precocious puberty caused by hCG-producing germinoma involving the bilateral basal ganglia and cerebral white matter without 1ypical radiologic findings: case report].},
  author={Shinichiro Sugiyama and T Kumabe and Masaki Mino and M Fujimura and Ikuma Fujiwara and Teiji Tominaga},
  journal={No shinkei geka. Neurological surgery},
  year={2006},
  volume={34 6},
  pages={619-24}
}
An 8-year-old boy presented with a rare case of germinoma involving the bilateral basal ganglia and cerebral white matter manifesting as precocious puberty. Magnetic resonance (MR) imaging at the initial presentation demonstrated mild hyperintense areas in the bilateral basal ganglia and corpus callosum on T1-weighted images, and a small hyperintense spot in the right internal capsule on T2-weighted images. Human chorionic gonadotropin (hCG) level was elevated in the cerebrospinal fluid (CSF… CONTINUE READING

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Magnetic resonance ( MR ) imaging at the initial presentation demonstrated mild hyperintense areas in the bilateral basal ganglia and corpus callosum on T1-weighted images , and a small hyperintense spot in the right internal capsule on T2-weighted images .
Magnetic resonance ( MR ) imaging at the initial presentation demonstrated mild hyperintense areas in the bilateral basal ganglia and corpus callosum on T1-weighted images , and a small hyperintense spot in the right internal capsule on T2-weighted images .
After three cycles of combination chemotherapy consisting of ifosfamide , cisplatin , and etoposide , followed by whole brain irradiation with a total dose of 24 Gy , the CSF hCG level fell below the detection limit , but MR imaging demonstrated no significant change .
After three cycles of combination chemotherapy consisting of ifosfamide , cisplatin , and etoposide , followed by whole brain irradiation with a total dose of 24 Gy , the CSF hCG level fell below the detection limit , but MR imaging demonstrated no significant change .
After three cycles of combination chemotherapy consisting of ifosfamide , cisplatin , and etoposide , followed by whole brain irradiation with a total dose of 24 Gy , the CSF hCG level fell below the detection limit , but MR imaging demonstrated no significant change .
After three cycles of combination chemotherapy consisting of ifosfamide , cisplatin , and etoposide , followed by whole brain irradiation with a total dose of 24 Gy , the CSF hCG level fell below the detection limit , but MR imaging demonstrated no significant change .
After three cycles of combination chemotherapy consisting of ifosfamide , cisplatin , and etoposide , followed by whole brain irradiation with a total dose of 24 Gy , the CSF hCG level fell below the detection limit , but MR imaging demonstrated no significant change .
After three cycles of combination chemotherapy consisting of ifosfamide , cisplatin , and etoposide , followed by whole brain irradiation with a total dose of 24 Gy , the CSF hCG level fell below the detection limit , but MR imaging demonstrated no significant change .
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