[Preclinical investigation of Mn(II)-diethylenetriaminepentaacetate (Mangapentetate) as paramagnetic contrast agent for magnetic resonance tomography].


The preclinical evaluation of 0.5 M solution of a manganese(II)-DTPA complex (Mangapentetate, Pentamang) has been carried out in order to test the ability of manganese to be used as substitute for potentially toxic gadolinium in paramagnetic contrast agents in the MRI clinical routines. The toxicologic tests of the Mn(II) - DTPA were carried out in mice… (More)


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