• Medicine
  • Published in
    Masui. The Japanese journal…
    1994

[Potentiation of pancuronium induced neuromuscular blockade by nitrous oxide].

@article{Tsuchiya1994PotentiationOP,
  title={[Potentiation of pancuronium induced neuromuscular blockade by nitrous oxide].},
  author={Atsushi Tsuchiya},
  journal={Masui. The Japanese journal of anesthesiology},
  year={1994},
  volume={43 9},
  pages={
          1322-7
        }
}
To evaluate in man the potentiation by nitrous oxide of the neuromuscular blockade produced by pancuronium, pancuronium 0.025, 0.035, 0.049 or 0.068 mg.kg-1 was given during thiamylal-fentanyl anesthesia with and without nitrous oxide, and the evoked electromyography (EMG) of hypothenar muscle was measured. In the group receiving nitrous oxide the ED50 and ED95 were 0.0359 and 0.0691 mg.kg-1. In the group not receiving nitrous oxide, these values were 0.0389 and 0.0849 mg.kg-1. The dose… CONTINUE READING